JULY 7, 2016
Citrulline Malate is a compound consisting of Citrulline, a nonessential amino acid that is primarily found in melons, and malate, an apple derivative. Citrulline, although a non-essential amino acid, is not widely abundant in our daily diet. However, it plays a vital role in many important biological processes.
For the past 20 years, Citrulline Malate has been used to treat fatigue, muscle weakness and Dementia. Dementia is a mental disorder that affects your ability to think, speak and move. Citrulline Malate has been used with great success by clinicians as a natural antiasthenic, with reported results of increased energy and overall feelings of well-being. L-Citrulline Malate benefits your performance at the gym by enhancing amino acid utilization in skeletal muscle and increasing blood flow while supporting ATP production. After absorption, citrulline either maintains its structure or gets converted to arginine, an amino acid commonly consumed to enhance strength and endurance. Additionally, arginine may improve mental clarity, alertness, & memory due to it being an intermediate in brain protein synthesis. L-Arginine metabolism in the brain is very important for normal brain function. Due to the citrulline component of citrulline malate acting as a precursor to arginine and ornithine, when necessitated, it must undergo conversion to either of the aforementioned amino acids in the kidneys. This amino acid conversion takes time, which causes the increase in plasma arginine to represent a curve vs. a peak. A sustained period of increased blood flow is what allows L-citrulline malate to not only increase your performance at the gym, but also aid recovery outside of the gym as well.
Growth hormone levels post-workout have been shown to increase by 66.8% in groups consuming citrulline malate vs. placebo. The enhanced growth hormone production is likely due to citrulline converting to arginine, which naturally blocks the binding of the hormone that inhibits GH production, somatostatin In essence, L-citrulline indirectly prevents growth hormone production from being blocked by increasing plasma arginine. Several clinical studies suggest that supplementation with L-citrulline malate may improve the health of your arteries and heart. L-citrulline malate supplements are available as pills from health food stores and some pharmacies. Because citrulline is a natural amino acid, it’s generally considered safe and without significant side effects.